Assay of dengue virus in monkey kidney cells by detection of hemagglutinin in the culture medium.

نویسنده

  • R S Goldsmith
چکیده

Tissue culture methods for the isolation and assay of the dengue viruses have been developed in a number of laboratories (1-7). Their aim has been to find an in vitro substitute for the suckling mouse (the usual host for these procedures). This study introduces a new method for the assay of mouse-adapted dengue viruses. Titrations and neutralization tests for serotypes 1, 2 and 4 have been conducted in test tube cultures of primary monkey kidney cells by a procedure using hemagglutination as the virus detection technique. This hemagglutination-virusdetection (HVD) procedure is based

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عنوان ژورنال:
  • American journal of epidemiology

دوره 84 2  شماره 

صفحات  -

تاریخ انتشار 1966